Juläine - The Bio Activator For Your Cells.

JULÄINE™ is a new solution in the field of regenerative aesthetics injectables. Our approach is simply to reveal the beauty that already exists within each and every one of us by supporting the body’s natural ability to regenerate and rejuvenate. Through a strong belief in the power of natural regeneration and dedicated scientific research, JULÄINE™ was created to re-activate the natural collagen production*, smoothening wrinkles and tightening the skin.

Developed with the unique LASYNPRO™ microsphere technology, JULÄINE™ uses the regenerative potential of Lactic Acid to deliver long-lasting, natural-looking results that feel authentic and real. The JULÄINE™ formula ensures the progressive and effective correction of lines and wrinkles ** through collagen regeneration in a natural way.

* By harnessing the power of mechanical signaling — a process that triggers the skin’s own renewal from within.

** JULÄINE™ is an injectable implant for adult immune-competent individuals. It is intended for the correction of mild to severe nasolabial folds.

Juläine Injectable - Collagen Biostimulator | Thames Skin Clinic Twickenham

Juläine Injectable

Revolutionary Swedish Collagen Biostimulator

Experience natural, long-lasting facial rejuvenation with next-generation PLLA technology. Transform your skin from within.

What is Juläine?

Juläine is a next-generation poly-L-lactic acid (PLLA) collagen biostimulator developed by Swedish biotech company Nordberg Medical. Unlike traditional dermal fillers that add temporary volume, Juläine works at the cellular level to activate your skin's natural regenerative processes.

The Science Behind Juläine

Juläine contains 150mg of high-purity PLLA microspheres engineered with proprietary LASYNPRO™ technology (Lactic-Acid Induced Synthesis of Collagen Protein). Once injected, these uniform microspheres gently activate fibroblasts—the cells responsible for collagen production—stimulating your body to rebuild its own collagen network from within.

As the PLLA microspheres gradually dissolve over 18-24 months, they release lactic acid, a powerful regenerative signaling molecule that the body naturally metabolises into CO₂ and water. What remains is stronger, revitalized skin with improved elasticity, firmness, and texture.

Nordberg Medical Expertise

Founded at Stockholm's prestigious Karolinska Science Park, Nordberg Medical specializes in developing biocompatible, biodegradable medical devices based on regenerative biomaterial science. Juläine represents the culmination of years of advanced research in collagen biology and aesthetic regeneration.

London & Twickenham Area

Thames Skin Clinic is proud to bring Juläine to patients in Twickenham, London, and surrounding areas. Our clinicians have completed comprehensive Juläine training, ensuring optimal injection techniques and personalized treatment protocols tailored to your aesthetic goals.

Real Results at 2 Months

Visible nasolabial fold improvement after first injection

Juläine before and after results showing nasolabial fold reduction at 2 months post-treatment

Proven Results Timeline

2-3 Months

Visible improvements in skin quality and reduction of fine lines

6+ Months

Optimal collagen regeneration and full aesthetic effect realized

18-24 Months

Long-lasting benefits continue as microspheres maintain structural support

25+ Years

PLLA's proven safety history in aesthetic medicine

Why Choose Juläine?

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Swedish Innovation

Developed by Nordberg Medical in Sweden using proprietary LASYNPRO™ technology for superior regenerative results.

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Long-Lasting Results

Results continue to improve for up to 6 months, with benefits lasting 18-24 months—double the duration of traditional fillers.

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Natural Appearance

Stimulates your body's own collagen production, avoiding the "overfilled" look. Progressive, subtle enhancement that looks genuinely refreshed.

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Clinically Proven

CE-marked in Europe with strong clinical evidence supporting safety, efficacy, and long-term collagen regeneration.

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Minimal Downtime

Mild redness or swelling typically resolves within days. Quick recovery means you can return to your routine immediately.

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Versatile Treatment

Excellent for nasolabial folds, marionette lines, jawline definition, and overall skin quality improvement across multiple facial areas.

How Juläine Works

Immediate Support

Juläine is carefully injected into targeted areas, providing gentle tissue support while the PLLA microspheres begin their regenerative work.

Fibroblast Activation (1-2 weeks)

A controlled, low-inflammatory response activates fibroblasts, signalling your skin cells to initiate collagen synthesis.

Progressive Improvement (2-6 months)

New collagen networks form throughout the treated area. Patients notice gradual improvement in skin elasticity, firmness, and quality.

Complete Degradation (18-24 months)

PLLA microspheres fully degrade into harmless lactic acid and water, leaving behind a strengthened collagen matrix that continues supporting your skin for over two years.

Key Benefits

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Smooths Fine Lines & Wrinkles

Reduces nasolabial folds, marionette lines, and age-related creasing

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Improves Skin Elasticity

Rebuilds the skin's structural framework for firmer, more resilient texture

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Enhances Skin Quality

Patients report improved hydration, radiance, and overall skin health

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Tightens & Lifts

Delivers a natural lift effect without artificial volume or a "done" appearance

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Addresses Skin Laxity

Ideal for patients concerned about loss of volume due to aging or weight loss

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Works on All Skin Types

Safe and effective for all ethnicities (Fitzpatrick I-VI) and skin tones

Advanced LASYNPRO™ Technology

Juläine's superiority lies in its proprietary LASYNPRO™ microsphere technology—a breakthrough in collagen biostimulation science:

Uniform Microsphere Design – Unlike other PLLA products, Juläine's microspheres are precisely engineered for consistent size and purity, ensuring smooth integration and predictable results
Low-Inflammatory Pathway – Activates collagen production while minimizing inflammatory response, reducing risk of nodules or granuloma formation
Controlled Release – Gradual degradation over 18-24 months provides sustained, continuous collagen stimulation rather than a single-dose effect
Biocompatible & Biodegradable – PLLA naturally breaks down into lactic acid (a powerful regenerative signaling molecule) and metabolises safely through normal body processes
Superior Safety Profile – CE-marked in Europe, manufactured to ISO 13485:2016 standards, with extensive preclinical and clinical testing supporting biocompatibility
Next-Generation Formula – Contains 150mg PLLA microspheres + 45mg sodium carboxymethylcellulose + 145mg mannitol for optimal reconstitution and injection comfort

As lactic acid is recognized as a multifunctional signaling molecule—not merely an inert byproduct—Juläine harnesses this powerful regenerative chemistry to reactivate your skin's youthful renewal processes.

Ready to Transform Your Skin?

Discover the future of natural facial rejuvenation with Juläine at Thames Skin Clinic

Book Your Consultation Today